143 次染色質(zhì)開放性測序(ATAC-seq)原理以及應(yīng)用領(lǐng)域 2025-4-30
技術(shù)簡介染色質(zhì)開放性測序(Assay for Transposase-Accessible Chromatin using sequencing,ATAC-seq),一種用于檢測染色質(zhì)開放性的高通量測序技術(shù),通過Tn5轉(zhuǎn)座酶切割并標(biāo)記開放的染色質(zhì)區(qū)域
162 次ATAC-seq開啟新視角:探索Shox2基因沙漠的神秘功能 2025-4-30
2024年7月,發(fā)表在《Nature Communications》的一篇文章“A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival”,聚焦Shox2基因
213 次機械拉伸誘導(dǎo)的活性氧驅(qū)動新生豬腎上皮細(xì)胞內(nèi)皮素的產(chǎn)生 2025-4-27
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cellsKeywords: Acute kidney injury; Endothelin; Endothelin
237 次Hes1/Piezo1 通路在糖皮質(zhì)激素誘導(dǎo)的骨質(zhì)疏松癥中的關(guān)鍵作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮質(zhì)激素
358 次DAP-seq技術(shù)助力揭示擬南芥根基本組織發(fā)育的調(diào)控機制 2025-4-21
2024 年 11月 18 日,蘭州大學(xué)黎家教授團隊在《Current Biology》(IF=8.1)發(fā)表了題為“Three RLKs integrate SHR-SCR and gibberellins to regulate root ground tissue patterning in A